![]() Other symptoms include cataplexy (the sudden loss of voluntary muscle tone, often triggered by strong emotions such as surprise, laughter or anger), which may cause them to lose their grip on things they are holding, or go completely limp and fall to the ground. ![]() EDS can also cause memory lapses, lack of concentration, fatigue, irritability, depression and exhaustion. Sleep episodes can last from seconds to minutes – obviously a danger for individuals who drive or operate hazardous machinery. The main symptom of narcolepsy is excessive daytime sleepiness (EDS), which often causes an individual to fall asleep without warning. REM patterns almost immediately after falling asleep at nighttime as well as throughout the day. The symptoms of narcolepsy mimic body changes that occur during normal REM – loss of muscle tone, inability to move, and dreaming. In most people, REM sleep usually occupies about 25 percent of total sleep time, and coincides with vividly recalled dreaming periods. The normal sleep cycle occurs as the sun goes down and is marked by progressive levels of sedation with deepening muscle relaxation and a slowing of brain waves (non REM sleep) this is followed by REM sleep with dreaming, suppression of muscle tone and high brain activity. ![]() Narcolepsy is thought to be a result of aberrant regulation of Rapid-Eye Movement (REM) sleep, a stage of normal sleeping during which the eyes are in almost continuous motion beneath closed lids. ![]()
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